Guarnacci, Marco and Preiss, Thomas (2024) The je ne sais quoi of 5-methylcytosine in messenger RNA. RNA, 30 (5). pp.560-569. ISSN 1355-8382
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Link to published document: http://doi.org/10.1261/rna.079982.124
Abstract
The potential presence of 5-methylcytosine as a sparse internal modification of mRNA was first raised in 1975, and a first map of the modification was also part of the epitranscriptomics "big bang" in 2012. Since then, the evidence for its presence in mRNA has firmed up, and initial insights have been gained into the molecular function and broader biological relevance of 5-methylcytosine when present in mRNA. Here, we summarize the status quo of the field, outline some of its current challenges, and suggest how to address them in future work.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Repository Administrator |
| Date Deposited: | 15 Dec 2024 04:14 |
| Last Modified: | 15 Dec 2024 04:16 |
| URI: | https://eprints.victorchang.edu.au/id/eprint/1528 |
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