Generation of an induced pluripotent stem cell line from an unaffected female whose two sisters suffered spontaneous coronary artery dissections (SCAD) (VCCRIi024-A)

Bax, Monique and Junday, Keerat and Hurley, Emily and Hesselson, Stephanie and McGrath-Cadell, Lucy and Kaidonis, Xenia and Tarr, Ingrid and Giannoulatou, Eleni and Iismaa, Siiri E. and Graham, Robert M. (2025) Generation of an induced pluripotent stem cell line from an unaffected female whose two sisters suffered spontaneous coronary artery dissections (SCAD) (VCCRIi024-A). Stem Cell Research, 87. p. 103770. ISSN 18735061

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Link to published document: https://doi.org/10.1016/j.scr.2025.103770

Abstract

Spontaneous Coronary Artery Dissection (SCAD) is a poorly understood predominantly female condition that can cause myocardial infarction, often affecting otherwise healthy women. Here, we generated an induced pluripotent stem cell line from a female with two SCAD-affected sisters. This individual has not had a SCAD to date; she is currently 12 years older than when SCAD first manifested in her sisters. This resource provides a valuable control for investigating mechanisms underlying SCAD susceptibility.

Item Type:	Article
Subjects:	R Medicine > R Medicine (General)
Depositing User:	Repository Administrator
Date Deposited:	03 Nov 2025 02:25
Last Modified:	03 Nov 2025 02:25
URI:	http://eprints.victorchang.edu.au/id/eprint/1734

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