Items where Author is "Windley, Monique J"

Article

Ng, Chai-Ann and Farr, Jessica and Young, Paul and Windley, Monique J and Perry, Matthew D and Hill, Adam P and Vandenberg, Jamie I (2021) Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology. Biology Methods and Protocols, 6 (1). ISSN 2396-8923

Lee, William and Windley, Monique J and Perry, Matthew D and Vandenberg, Jamie I and Hill, Adam (2019) Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding. Molecular Pharmacology, ePub. pp. mol.118.115220. ISSN 0026-895X (OA)

Munawar, Saba and Windley, Monique J and Tse, Edwin G and Todd, Matthew H and Hill, Adam P and Vandenberg, Jamie I and Jabeen, Ishrat (2018) Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities. Frontiers in Pharmacology, 9. ISSN 1663-9812 (Not OA)

Windley, Monique J and Lee, William and Vandenberg, Jamie I and Hill, Adam P (2018) The temperature dependence of kinetics associated with drug block of hERG channels are compound specific and an important factor for proarrhythmic risk prediction. Molecular Pharmacology, 94 (1). pp.760-769. ISSN 1521-0111 (PP OA)

Lee, William and Windley, Monique J and Vandenberg, Jamie I and Hill, Adam P (2017) In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details. Frontiers in Physiology, 8. p. 934. ISSN 1664-042X (OA)

Windley, Monique J and Abi-Gerges, Najah and Fermini, Bernard and Hancox, Jules C and Vandenberg, Jamie I and Hill, Adam P (2017) Measuring kinetics and potency of hERG block for CiPA. Journal of Pharmacological and Toxicological Methods, 87. pp.99-107. ISSN 1873-488X (PP OA)

Windley, Monique J and Mann, Stefan A and Vandenberg, Jamie I and Hill, Adam P (2016) Temperature effects on kinetics of Kv11.1 drug block have important consequences for in silico proarrhythmic risk prediction. Molecular Pharmacology, 90 (1). pp.1-11. ISSN 1521-0111 (OA)

Lee, William and Mann, Stefan A and Windley, Monique J and Imtiaz, Mohammad S and Vandenberg, Jamie I and Hill, Adam P (2016) In silico assessment of kinetics and state dependent binding properties of drugs causing acquired LQTS. Progress in Biophysics and Molecular Biology, 120 (1-3). pp.89-99. ISSN 1873-1732 (Not OA)