Items where Author is "Smith, Nicola J"
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Machet, Joshua and Park, Mijeong and Richardson, Alexander and Carnell, Michael and Mouat, Margaret A and Smith, Nicola J and Turner, Nigel and Cochran, Blake J and Rye, Kerry‐Anne and Di Girolamo, Nick (2023) Type 2 diabetes influences intraepithelial corneal nerve parameters and corneal stromal‐epithelial nerve penetration sites. Journal of Diabetes Investigation, 14 (4). pp.591-601. ISSN 2040-1116
Sobti, Meghna and Ishmukhametov, Robert and Bouwer, James C and Ayer, Anita and Suarna, Cacang and Smith, Nicola J and Christie, Mary and Stocker, Roland and Duncan, Thomas M and Stewart, Alastair G (2019) Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP. eLife, 8 (epub). ISSN 2050-084X
Coleman, James L J and Mouat, Margaret A and Wu, Jianxin and Jancovski, Nikola and Bassi, Jaspreet K and Chan, Andrea Y and Humphreys, David T and Mrad, Nadine and Yu, Ze-Yan and Ngo, Tony and Iismaa, Siiri and Dos Remedios, Cristobal G and Feneley, Michael P and Allen, Andrew M and Graham, Robert M and Smith, Nicola J (2018) Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control. Biology of Sex Differences, 9 (1). p. 14. ISSN 2042-6410 (OA)
Mouat, Margaret A and Coleman, James L J and Smith, Nicola J (2018) GPCRS IN CONTEXT: SEXUAL DIMORPHISM IN THE CARDIOVASCULAR SYSTEM. British Journal of Pharmacology, 175. pp.4047-4059. ISSN 00071188 (PP OA)
Wirasinha, R C and Vijayan, D and Smith, Nicola J and Parnell, G P and Swarbrick, A and Brink, R and King, C and Stewart, G and Booth, D R and Batten, M (2018) GPR65 inhibits experimental autoimmune encephalomyelitis through CD4+ T cell independent mechanisms that include effects on iNKT cells. Immunology and Cell Biology, 96 (2). pp.128-136. ISSN 08189641 (Not OA)
Coleman, James L J and Ngo, Tony and Smith, Nicola J (2017) The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era. Cellular Signalling, 33. pp.1-9. ISSN 1873-3913 (PP OA)
Ngo, Tony and Ilatovskiy, Andrey V and Stewart, Alastair G and Coleman, James L J and McRobb, Fiona M and Riek, R Peter and Graham, Robert M and Abagyan, Ruben and Kufareva, Irina and Smith, Nicola J (2017) Orphan receptor ligand discovery by pickpocketing pharmacological neighbors. Nature Chemical Biology, 13 (2). pp.235-242. ISSN 1552-4469 (PMC OA)
Chowdhury, Md Kamrul H and Wu, Lindsay E and Coleman, James L J and Smith, Nicola J and Morris, Margaret J and Shepherd, Peter R and Smith, Greg C (2016) Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling. The Biochemical Journal, 473 (9). pp.1247-55. ISSN 1470-8728 (OA)
Coleman, James L J and Ngo, Tony and Schmidt, Johannes and Mrad, Nadine and Liew, Chu Kong and Jones, Nicole M and Graham, Robert M and Smith, Nicola J (2016) Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity. Science Signaling, 9 (423). pp. ra36. ISSN 1937-9145 (OA)
McNamara, James W and Li, Amy and Smith, Nicola J and Lal, Sean and Graham, Robert M and Kooiker, Kristina Bezold and van Dijk, Sabine J and Remedios, Cristobal G Dos and Harris, Samantha P and Cooke, Roger (2016) Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes. Journal of Molecular and Cellular Cardiology, 94. pp.65-71. ISSN 1095-8584 (PMC OA)
Soetanto, Rina and Hynes, Carly J and Patel, Hardip R and Humphreys, David T and Evers, Maurits and Duan, Guowen and Parker, Brian J and Archer, Stuart K and Clancy, Jennifer L and Graham, Robert M and Beilharz, Traude H and Smith, Nicola J and Preiss, Thomas (2016) Role of miRNAs and alternative mRNA 3'-end cleavage and polyadenylation of their mRNA targets in cardiomyocyte hypertrophy. Biochimica et Biophysica Acta, 1859 (5). pp.744-756. ISSN 0006-3002 (PP OA)
Grundmann, Manuel and Tikhonova, Irina G and Hudson, Brian D and Smith, Nicola J and Mohr, Klaus and Ulven, Trond and Milligan, Graeme and Kenakin, Terry and Kostenis, Evi (2016) A Molecular Mechanism for Sequential Activation of a G Protein-Coupled Receptor. Cell Chemical Biology, 23 (3). pp.392-403. ISSN 2451-9456 (OA)
Ngo, Tony and Kufareva, Irina and Coleman, James L J and Graham, Robert M and Abagyan, Ruben and Smith, Nicola J (2016) Identifying ligands at orphan GPCRs: current status using structure-based approaches. British Journal of Pharmacology, 173 (20). pp.2934-2951. ISSN 1476-5381 (OA)
Smith, Nicola J (2015) Drug Discovery Opportunities at the Endothelin B Receptor-Related Orphan G Protein-Coupled Receptors, GPR37 and GPR37L1. Frontiers in Pharmacology, 6. p. 275. ISSN 1663-9812 (OA)
Foster, Simon R and Porrello, Enzo R and Stefani, Maurizio and Smith, Nicola J and Molenaar, Peter and dos Remedios, Cristobal G and Thomas, Walter G and Ramialison, Mirana (2015) Cardiac gene expression data and in silico analysis provide novel insights into human and mouse taste receptor gene regulation. Naunyn-Schmiedeberg's Archives of Pharmacology, 388 (10). pp.1009-27. ISSN 1432-1912 (Not OA)
Coleman, James L J and Brennan, Karen and Ngo, Tony and Balaji, Poornima and Graham, Robert M and Smith, Nicola J (2015) Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study. Frontiers in Endocrinology, 6. p. 105. ISSN 1664-2392 (OA)
Ngo, Tony and Coleman, James L J and Smith, Nicola J (2015) Using constitutive activity to define appropriate high-throughput screening assays for orphan G protein-coupled receptors. Methods in Molecular Biology, 1272. pp.91-106. ISSN 1940-6029 (Book Chapter _OA Not required)
Yu, Ze-Yan and Tan, Ju-Chiat and McMahon, Aisling C and Iismaa, Siiri E and Xiao, Xiao-Hui and Kesteven, Scott H and Reichelt, Melissa E and Mohl, Marion C and Smith, Nicola J and Fatkin, Diane and Allen, David and Head, Stewart I and Graham, Robert M and Feneley, Michael P (2014) RhoA/ROCK signaling and pleiotropic α1A-adrenergic receptor regulation of cardiac contractility. PloS One, 9 (6). pp. e99024. ISSN 1932-6203 (Gold OA)
Smith, Nicola J (2012) Low affinity GPCRs for metabolic intermediates: challenges for pharmacologists. Frontiers in endocrinology, 3. p. 1. ISSN 1664-2392 (OA)