Items where Author is "Perry, Matthew D"

Article

Ballouz, Sara and Mangala, Melissa M and Perry, Matthew D and Heitmann, Stewart and Gillis, Jesse A and Hill, Adam P and Vandenberg, Jamie I (2021) Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events. Cardiovascular Research, 117 (10). pp.2216-2227. ISSN 0008-6363

Ng, Chai-Ann and Farr, Jessica and Young, Paul and Windley, Monique J and Perry, Matthew D and Hill, Adam P and Vandenberg, Jamie I (2021) Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology. Biology Methods and Protocols, 6 (1). ISSN 2396-8923

Perry, Matthew D and Ng, Chai-Ann and Mangala, Melissa M and Ng, Timothy Y M and Hines, Adam D and Liang, Whitney and Xu, Michelle J O and Hill, Adam P and Vandenberg, Jamie I (2020) Pharmacological activation of IKr in models of long QT Type 2 risks overcorrection of repolarization. Cardiovascular Research, 116 (8). pp.1434-1445. ISSN 0008-6363

Lee, William and Windley, Monique J and Perry, Matthew D and Vandenberg, Jamie I and Hill, Adam (2019) Protocol-dependent differences in IC50 values measured in hERG assays occur in a predictable way and can be used to quantify state preference of drug binding. Molecular Pharmacology, ePub. pp. mol.118.115220. ISSN 0026-895X (OA)

Vandenberg, Jamie I and Perry, Matthew D and Hill, Adam P (2017) Recent advances in understanding and prevention of sudden cardiac death. F1000Research, 6. p. 1614. ISSN 2046-1402 (OA)

Phan, Kevin and Ng, Chai Ann and David, Erikka and Shishmarev, Dmitry and Kuchel, Philip W and Vandenberg, Jamie I and Perry, Matthew D (2017) The S1 Helix Critically Regulates the Finely-tuned Gating of Kv11.1 Channels. The Journal of Biological Chemistry, 292 (18). pp.7688-7705. ISSN 1083-351X (OA)

Perry, Matthew D and Vandenberg, Jamie I (2016) TECRL: connecting sequence to consequence for a new sudden cardiac death gene. EMBO Molecular Medicine, 8. pp.1364-1365. ISSN 1757-4684 (OA)

Mann, Stefan A and Imtiaz, Mohammad and Winbo, Annika and Rydberg, Annika and Perry, Matthew D and Couderc, Jean-Philippe and Polonsky, Bronislava and McNitt, Scott and Zareba, Wojciech and Hill, Adam P and Vandenberg, Jamie I (2016) Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes. Journal of Molecular and Cellular Cardiology, 100. pp.25-34. ISSN 1095-8584 (PP OA)

Ng, Chai-Ann and Gravel, Andrée E and Perry, Matthew D and Arnold, Alexandre A and Marcotte, Isabelle and Vandenberg, Jamie I (2016) Tyrosine residues from the S4-S5 linker of Kv11.1 channels are critical for slow deactivation. The Journal of Biological Chemistry, 291. pp.17293-17302. ISSN 1083-351X (OA)

Hill, Adam P and Perry, Matthew D and Abi-Gerges, Najah and Couderc, Jean-Philippe and Fermini, Bernard and Hancox, Jules C and Knollmann, Bjorn C and Mirams, Gary R and Skinner, Jon and Zareba, Wojciech and Vandenberg, Jamie I (2016) Computational Cardiology and Risk Stratification for Sudden Cardiac Death: One of the Grand Challenges for Cardiology in the 21(st) Century. The Journal of Physiology, 594 (23). pp.6893-6908. ISSN 1469-7793 (OA)

Perry, Matthew D and Ng, Chai Ann and Phan, Kevin and David, E and Steer, K and Hunter, Mark J and Mann, Stefan A and Imtiaz, Mohammad S and Hill, Adam P and Ke, Ying and Vandenberg, Jamie I (2016) Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations. The Journal of Physiology, 594 (14). pp.4031-4049. ISSN 1469-7793 (PMC OA)

Fonoudi, Hananeh and Ansari, Hassan and Abbasalizadeh, Saeed and Larijani, Mehran Rezaei and Kiani, Sahar and Hashemizadeh, Shiva and Zarchi, Ali Sharifi and Bosman, Alexis and Blue, Gillian M and Pahlavan, Sara and Perry, Matthew D and Orr, Yishay and Mayorchak, Yaroslav and Vandenberg, Jamie I and Talkhabi, Mahmood and Winlaw, David S and Harvey, Richard P and Aghdami, Nasser and Baharvand, Hossein (2015) A Universal and Robust Integrated Platform for the Scalable Production of Human Cardiomyocytes From Pluripotent Stem Cells. Stem Cells Translational Medicine, 4 (12). pp.1482-94. ISSN 2157-6564 (PP OA)

Perry, Matthew D and Ng, Chai-Ann and Mann, Stefan A and Sadrieh, Arash and Imtiaz, Mohammad and Hill, Adam P and Vandenberg, Jamie I (2015) Getting to the heart of hERG K(+) channel gating. The Journal of Physiology, 593 (12). pp.2575-85. ISSN 1469-7793 (PMC OA)

Vandenberg, Jamie I and Perry, Matthew D (2014) Can many subunits make light work of ion channel inactivation? The Journal of Physiology, 592 (Pt 20). pp.4411-2. ISSN 1469-7793 (OA)

Ng, Chai Ann and Phan, Kevin and Hill, Adam P and Vandenberg, Jamie I and Perry, Matthew D (2014) Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels. The Journal of Biological Chemistry, 289 (37). pp.25822-32. ISSN 1083-351X (PMC OA)

Ke, Ying and Hunter, Mark J and Ng, Chai Ann and Perry, Matthew D and Vandenberg, Jamie I (2014) Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels. The Journal of Biological Chemistry, 289 (20). pp.13782-91. ISSN 1083-351X (OA)

Sadrieh, Arash and Domanski, Luke and Pitt-Francis, Joe and Mann, Stefan A and Hodkinson, Emily C and Ng, Chai-Ann and Perry, Matthew D and Taylor, John A and Gavaghan, David and Subbiah, Rajesh N and Vandenberg, Jamie I and Hill, Adam P (2014) Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2. Nature Communications, 5. p. 5069. ISSN 2041-1723 (OA)

Perry, Matthew D and Wong, Sophia and Ng, Chai Ann and Vandenberg, Jamie I (2013) Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels. The Journal of general physiology, 142 (3). pp.275-88. ISSN 1540-7748 (PMC OA)

Perry, Matthew D and Ng, Chai Ann and Vandenberg, Jamie I (2013) Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating. The Journal of biological chemistry, 288 (16). pp.11482-91. ISSN 1083-351X (PMC OA)

Ng, Chai Ann and Ke, Ying and Perry, Matthew D and Tan, Peter S and Hill, Adam P and Vandenberg, Jamie I (2013) C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels. PloS one, 8 (10). pp. e77032. ISSN 1932-6203 (Gold OA)

Tan, Peter S and Perry, Matthew D and Ng, Chai Ann and Vandenberg, Jamie I and Hill, Adam P (2012) Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels. The Journal of general physiology, 140 (3). pp.293-306. ISSN 1540-7748 (PMC OA)

Vandenberg, Jamie I and Perry, Matthew D and Perrin, Mark J and Mann, Stefan A and Ke, Ying and Hill, Adam P (2012) hERG K(+) channels: structure, function, and clinical significance. Physiological reviews, 92 (3). pp.1393-478. ISSN 1522-1210 (OA)

Ng, Chai Ann and Perry, Matthew D and Tan, Peter S and Hill, Adam P and Kuchel, Philip W and Vandenberg, Jamie I (2012) The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating. PloS one, 7 (2). pp. e31640. ISSN 1932-6203 (Gold OA)