Items where Author is "Ngo, Tony"
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Ngo, Tony and Ilatovskiy, Andrey V. and Stewart, Alastair G. and Coleman, James L. J. and McRobb, Fiona M. and Riek, R. Peter and Graham, Robert M. and Abagyan, Ruben and Kufareva, Irina and Smith, Nicola J. (2021) RETRACTED: Orphan receptor ligand discovery by pickpocketing pharmacological neighbors. Nature Chemical Biology, 17 (4). p. 501. ISSN 1552-4450
Coleman, James L. J. and Ngo, Tony and Smythe, Rhyll E. and Cleave, Andrew J. and Jones, Nicole M. and Graham, Robert M. and Smith, Nicola J. (2020) The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases. Scientific Reports, 10 (1). ISSN 2045-2322
Coleman, James L J and Mouat, Margaret A and Wu, Jianxin and Jancovski, Nikola and Bassi, Jaspreet K and Chan, Andrea Y and Humphreys, David T and Mrad, Nadine and Yu, Ze-Yan and Ngo, Tony and Iismaa, Siiri and Dos Remedios, Cristobal G and Feneley, Michael P and Allen, Andrew M and Graham, Robert M and Smith, Nicola J (2018) Orphan receptor GPR37L1 contributes to the sexual dimorphism of central cardiovascular control. Biology of Sex Differences, 9 (1). p. 14. ISSN 2042-6410 (OA)
Naz, Sadia and Ngo, Tony and Farooq, Umar and Abagyan, Ruben (2017) Analysis of drug binding pockets and repurposing opportunities for twelve essential enzymes of ESKAPE pathogens. PeerJ, 5. pp. e3765. ISSN 2167-8359 (OA)
Coleman, James L J and Ngo, Tony and Smith, Nicola J (2017) The G protein-coupled receptor N-terminus and receptor signalling: N-tering a new era. Cellular Signalling, 33. pp.1-9. ISSN 1873-3913 (PP OA)
Ngo, Tony and Ilatovskiy, Andrey V and Stewart, Alastair G and Coleman, James L J and McRobb, Fiona M and Riek, R Peter and Graham, Robert M and Abagyan, Ruben and Kufareva, Irina and Smith, Nicola J (2017) Orphan receptor ligand discovery by pickpocketing pharmacological neighbors. Nature Chemical Biology, 13 (2). pp.235-242. ISSN 1552-4469 (PMC OA)
Coleman, James L J and Ngo, Tony and Schmidt, Johannes and Mrad, Nadine and Liew, Chu Kong and Jones, Nicole M and Graham, Robert M and Smith, Nicola J (2016) Metalloprotease cleavage of the N terminus of the orphan G protein-coupled receptor GPR37L1 reduces its constitutive activity. Science Signaling, 9 (423). pp. ra36. ISSN 1937-9145 (OA)
Ngo, Tony and Kufareva, Irina and Coleman, James L J and Graham, Robert M and Abagyan, Ruben and Smith, Nicola J (2016) Identifying ligands at orphan GPCRs: current status using structure-based approaches. British Journal of Pharmacology, 173 (20). pp.2934-2951. ISSN 1476-5381 (OA)
Coleman, James L J and Brennan, Karen and Ngo, Tony and Balaji, Poornima and Graham, Robert M and Smith, Nicola J (2015) Rapid Knockout and Reporter Mouse Line Generation and Breeding Colony Establishment Using EUCOMM Conditional-Ready Embryonic Stem Cells: A Case Study. Frontiers in Endocrinology, 6. p. 105. ISSN 1664-2392 (OA)
Ngo, Tony and Coleman, James L J and Smith, Nicola J (2015) Using constitutive activity to define appropriate high-throughput screening assays for orphan G protein-coupled receptors. Methods in Molecular Biology, 1272. pp.91-106. ISSN 1940-6029 (Book Chapter _OA Not required)
Thesis
Ngo, Tony (2017) Drug discovery at the orphan G protein-coupled receptor, GPR37L1. PhD thesis, Victor Chang Cardiac Research Institute.