Items where Author is "Ng, Chai Ann"
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Phan, Kevin and Ng, Chai Ann and David, Erikka and Shishmarev, Dmitry and Kuchel, Philip W and Vandenberg, Jamie I and Perry, Matthew D (2017) The S1 Helix Critically Regulates the Finely-tuned Gating of Kv11.1 Channels. The Journal of Biological Chemistry, 292 (18). pp.7688-7705. ISSN 1083-351X (OA)
Perry, Matthew D and Ng, Chai Ann and Phan, Kevin and David, E and Steer, K and Hunter, Mark J and Mann, Stefan A and Imtiaz, Mohammad S and Hill, Adam P and Ke, Ying and Vandenberg, Jamie I (2016) Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations. The Journal of Physiology, 594 (14). pp.4031-4049. ISSN 1469-7793 (PMC OA)
Ng, Chai Ann and Phan, Kevin and Hill, Adam P and Vandenberg, Jamie I and Perry, Matthew D (2014) Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels. The Journal of Biological Chemistry, 289 (37). pp.25822-32. ISSN 1083-351X (PMC OA)
Ke, Ying and Hunter, Mark J and Ng, Chai Ann and Perry, Matthew D and Vandenberg, Jamie I (2014) Role of the cytoplasmic N-terminal Cap and Per-Arnt-Sim (PAS) domain in trafficking and stabilization of Kv11.1 channels. The Journal of Biological Chemistry, 289 (20). pp.13782-91. ISSN 1083-351X (OA)
Perry, Matthew D and Wong, Sophia and Ng, Chai Ann and Vandenberg, Jamie I (2013) Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels. The Journal of general physiology, 142 (3). pp.275-88. ISSN 1540-7748 (PMC OA)
Ke, Ying and Ng, Chai Ann and Hunter, Mark J and Mann, Stefan A and Heide, Juliane and Hill, Adam P and Vandenberg, Jamie I (2013) Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions. The Biochemical journal, 454 (1). pp.69-77. ISSN 1470-8728 (OA)
Perry, Matthew D and Ng, Chai Ann and Vandenberg, Jamie I (2013) Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating. The Journal of biological chemistry, 288 (16). pp.11482-91. ISSN 1083-351X (PMC OA)
Ng, Chai Ann and Torres, Allan M and Pagès, Guilhem and Kuchel, Philip W and Vandenberg, Jamie I (2013) Insights into hERG K+ channel structure and function from NMR studies. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 42 (1). pp.71-9. ISSN 1432-1017 (Not OA)
Ng, Chai Ann and Ke, Ying and Perry, Matthew D and Tan, Peter S and Hill, Adam P and Vandenberg, Jamie I (2013) C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels. PloS one, 8 (10). pp. e77032. ISSN 1932-6203 (Gold OA)
Tan, Peter S and Perry, Matthew D and Ng, Chai Ann and Vandenberg, Jamie I and Hill, Adam P (2012) Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels. The Journal of general physiology, 140 (3). pp.293-306. ISSN 1540-7748 (PMC OA)
Ng, Chai Ann and Perry, Matthew D and Tan, Peter S and Hill, Adam P and Kuchel, Philip W and Vandenberg, Jamie I (2012) The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating. PloS one, 7 (2). pp. e31640. ISSN 1932-6203 (Gold OA)