Items where Author is "Mann, Stefan A"

Article

Mann, Stefan A and Imtiaz, Mohammad and Winbo, Annika and Rydberg, Annika and Perry, Matthew D and Couderc, Jean-Philippe and Polonsky, Bronislava and McNitt, Scott and Zareba, Wojciech and Hill, Adam P and Vandenberg, Jamie I (2016) Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes. Journal of Molecular and Cellular Cardiology, 100. pp.25-34. ISSN 1095-8584 (PP OA)

Windley, Monique J and Mann, Stefan A and Vandenberg, Jamie I and Hill, Adam P (2016) Temperature effects on kinetics of Kv11.1 drug block have important consequences for in silico proarrhythmic risk prediction. Molecular Pharmacology, 90 (1). pp.1-11. ISSN 1521-0111 (OA)

Perry, Matthew D and Ng, Chai Ann and Phan, Kevin and David, E and Steer, K and Hunter, Mark J and Mann, Stefan A and Imtiaz, Mohammad S and Hill, Adam P and Ke, Ying and Vandenberg, Jamie I (2016) Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations. The Journal of Physiology, 594 (14). pp.4031-4049. ISSN 1469-7793 (PMC OA)

Heide, Juliane and Zhang, Fengyu and Bigos, Kristin L and Mann, Stefan A and Carr, Vaughan J and Shannon Weickert, Cynthia and Green, Melissa J and Weinberger, Daniel R and Vandenberg, Jamie I (2016) Differential Response to Risperidone in Schizophrenia Patients by KCNH2 Genotype and Drug Metabolizer Status. The American Journal of Psychiatry, 173 (1). pp.53-9. ISSN 1535-7228 (OA)

Lee, William and Mann, Stefan A and Windley, Monique J and Imtiaz, Mohammad S and Vandenberg, Jamie I and Hill, Adam P (2016) In silico assessment of kinetics and state dependent binding properties of drugs causing acquired LQTS. Progress in Biophysics and Molecular Biology, 120 (1-3). pp.89-99. ISSN 1873-1732 (Not OA)

Perry, Matthew D and Ng, Chai-Ann and Mann, Stefan A and Sadrieh, Arash and Imtiaz, Mohammad and Hill, Adam P and Vandenberg, Jamie I (2015) Getting to the heart of hERG K(+) channel gating. The Journal of Physiology, 593 (12). pp.2575-85. ISSN 1469-7793 (PMC OA)

Hill, Adam P and Perrin, Mark J and Heide, Juliane and Campbell, Terence J and Mann, Stefan A and Vandenberg, Jamie I (2014) Kinetics of drug interaction with the Kv11.1 potassium channel. Molecular Pharmacology, 85 (5). pp.769-76. ISSN 1521-0111 (OA)

Liang, Bo and Soka, Magdalena and Christensen, Alex Horby and Olesen, Morten S and Larsen, Anders P and Knop, Filip K and Wang, Fan and Nielsen, Jonas B and Andersen, Martin N and Humphreys, David T and Mann, Stefan A and Huttner, Inken G and Vandenberg, Jamie I and Svendsen, Jesper H and Haunsø, Stig and Preiss, Thomas and Seebohm, Guiscard and Olesen, Søren-Peter and Schmitt, Nicole and Fatkin, Diane (2014) Genetic variation in the two-pore domain potassium channel, TASK-1, may contribute to an atrial substrate for arrhythmogenesis. Journal of Molecular and Cellular Cardiology, 67. pp.69-76. ISSN 1095-8584 (PP OA)

Sadrieh, Arash and Domanski, Luke and Pitt-Francis, Joe and Mann, Stefan A and Hodkinson, Emily C and Ng, Chai-Ann and Perry, Matthew D and Taylor, John A and Gavaghan, David and Subbiah, Rajesh N and Vandenberg, Jamie I and Hill, Adam P (2014) Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2. Nature Communications, 5. p. 5069. ISSN 2041-1723 (OA)

Sadrieh, Arash and Mann, Stefan A and Subbiah, Rajesh N and Domanski, Luke and Taylor, John A and Vandenberg, Jamie I and Hill, Adam P (2013) Quantifying the origins of population variability in cardiac electrical activity through sensitivity analysis of the electrocardiogram. The Journal of physiology, 591 (Pt 17). pp.4207-22. ISSN 1469-7793 (PMC OA)

Ke, Ying and Ng, Chai Ann and Hunter, Mark J and Mann, Stefan A and Heide, Juliane and Hill, Adam P and Vandenberg, Jamie I (2013) Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions. The Biochemical journal, 454 (1). pp.69-77. ISSN 1470-8728 (OA)

Huttner, Inken G and Trivedi, Gunjan and Jacoby, Arie and Mann, Stefan A and Vandenberg, Jamie I and Fatkin, Diane (2013) A transgenic zebrafish model of a human cardiac sodium channel mutation exhibits bradycardia, conduction-system abnormalities and early death. Journal of molecular and cellular cardiology, 61. pp.123-32. ISSN 1095-8584 (Not OA)

Mann, Stefan A and Castro, Maria L and Ohanian, Monique and Guo, Guanglan and Zodgekar, Poonam and Sheu, Angela and Stockhammer, Kathryn and Thompson, Tina and Playford, David and Subbiah, Rajesh and Kuchar, Dennis and Aggarwal, Anu and Vandenberg, Jamie I and Fatkin, Diane (2012) R222Q SCN5A mutation is associated with reversible ventricular ectopy and dilated cardiomyopathy. Journal of the American College of Cardiology, 60 (16). pp.1566-73. ISSN 1558-3597 (OA)

Vandenberg, Jamie I and Perry, Matthew D and Perrin, Mark J and Mann, Stefan A and Ke, Ying and Hill, Adam P (2012) hERG K(+) channels: structure, function, and clinical significance. Physiological reviews, 92 (3). pp.1393-478. ISSN 1522-1210 (OA)

Mann, Stefan A and Otway, Robyn and Guo, Guanglan and Soka, Magdalena and Karlsdotter, Lina and Trivedi, Gunjan and Ohanian, Monique and Zodgekar, Poonam and Smith, Robert A and Wouters, Merridee A and Subbiah, Rajesh and Walker, Bruce and Kuchar, Dennis and Sanders, Prashanthan and Griffiths, Lyn and Vandenberg, Jamie I and Fatkin, Diane (2012) Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk. Journal of the American College of Cardiology, 59 (11). pp.1017-25. ISSN 1558-3597 (OA)

Heide, Juliane and Mann, Stefan A and Vandenberg, Jamie I (2012) The schizophrenia-associated Kv11.1-3.1 isoform results in reduced current accumulation during repetitive brief depolarizations. PloS one, 7 (9). pp. e45624. ISSN 1932-6203 (Gold OA)