Items where Author is "Cox, Charles D."

Guo, Yang and Cheng, Delfine and Yu, Ze‐Yan and Schiatti, Teresa and Chan, Andrea Y. and Hill, Adam P. and Peyronnet, Rémi and Feneley, Michael P. and Cox, Charles D. and Martinac, Boris (2024) Functional coupling between Piezo1 and TRPM4 influences the electrical activity of HL‐1 atrial myocytes. The Journal of Physiology, 602 (18). pp.4363-4386. ISSN 0022-3751

Han, Yaoyao and Zhou, Zijing and Jin, Ruitao and Dai, Fei and Ge, Yifan and Ju, Xisan and Ma, Xiaonuo and He, Sitong and Yuan, Ling and Wang, Yingying and Yang, Wei and Yue, Xiaomin and Chen, Zhongwen and Sun, Yadong and Corry, Ben and Cox, Charles D. and Zhang, Yixiao (2024) Mechanical activation opens a lipid-lined pore in OSCA ion channels. Nature, 628 (8009). pp.910-918. ISSN 0028-0836

Wang, Haoqing Jerry and Wang, Yao and Mirjavadi, Seyed Sajad and Andersen, Tomas and Moldovan, Laura and Vatankhah, Parham and Russell, Blake and Jin, Jasmine and Zhou, Zijing and Li, Qing and Cox, Charles D. and Su, Qian Peter and Ju, Lining Arnold (2024) Microscale geometrical modulation of PIEZO1 mediated mechanosensing through cytoskeletal redistribution. Nature Communications, 15 (1). ISSN 2041-1723

Janbandhu, Vaibhao and Tallapragada, Vikram and Li, Jinyuan Vero and Shewale, Bharti and Ghazanfar, Shila and Patrick, Ralph and Cox, Charles D. and Harvey, Richard P. (2024) Novel Mouse Model for Selective Tagging, Purification, and Manipulation of Cardiac Myofibroblasts. Circulation, 149 (24). pp.1931-1934. ISSN 0009-7322

Cox, Charles D. and Poole, Kate and Martinac, Boris (2024) Re-evaluating TRP channel mechanosensitivity. Trends in Biochemical Sciences, 49 (8). pp.693-702. ISSN 09680004

Zhou, Zijing and Ma, Xiaonuo and Lin, Yiechang and Cheng, Delfine and Bavi, Navid and Secker, Genevieve A. and Li, Jinyuan Vero and Janbandhu, Vaibhao and Sutton, Drew L. and Scott, Hamish S. and Yao, Mingxi and Harvey, Richard P. and Harvey, Natasha L. and Corry, Ben and Zhang, Yixiao and Cox, Charles D. (2023) MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels. Science, 381 (6659). pp.799-804. ISSN 0036-8075

Zhang, Mingfeng and Shan, Yuanyue and Cox, Charles D. and Pei, Duanqing (2023) A mechanical-coupling mechanism in OSCA/TMEM63 channel mechanosensitivity. Nature Communications, 14 (1). ISSN 2041-1723

Bavi, Omid and Zhou, Zijing and Bavi, Navid and Mehdi Vaez Allaei, S. and Cox, Charles D. and Martinac, B. (2022) Asymmetric effects of amphipathic molecules on mechanosensitive channels. Scientific Reports, 12 (1). ISSN 2045-2322

Fatkin, Diane and Cox, Charles D. and Martinac, Boris (2022) Fishing for Links Between Omega-3 Fatty Acids and Atrial Fibrillation. Circulation, 145 (14). pp.1037-1039. ISSN 0009-7322

Wang, Haoqing and Obeidy, Peyman and Wang, Zihao and Zhao, Yunduo and Wang, Yao and Su, Qian Peter and Cox, Charles D. and Ju, Lining Arnold (2022) Fluorescence-coupled micropipette aspiration assay to examine calcium mobilization caused by red blood cell mechanosensing. European Biophysics Journal, 51 (2). pp.135-146. ISSN 0175-7571

Yao, Mingxi and Tijore, Ajay and Cheng, Delfine and Li, Jinyuan Vero and Hariharan, Anushya and Martinac, Boris and Tran Van Nhieu, Guy and Cox, Charles D. and Sheetz, Michael (2022) Force- and cell state–dependent recruitment of Piezo1 drives focal adhesion dynamics and calcium entry. Science Advances, 8 (45). ISSN 2375-2548

Chow, Pak Hin and Cox, Charles D. and Pei, Jinxin V. and Anabaraonye, Nancy and Nourmohammadi, Saeed and Henderson, Sam W. and Martinac, Boris and Abdulmalik, Osheiza and Yool, Andrea J. (2022) Inhibition of the Aquaporin-1 Cation Conductance by Selected Furan Compounds Reduces Red Blood Cell Sickling. Frontiers in Pharmacology, 12. ISSN 1663-9812

Lai, Austin and Cox, Charles D. and Chandra Sekar, Nadia and Thurgood, Peter and Jaworowski, Anthony and Peter, Karlheinz and Baratchi, Sara (2022) Mechanosensing by Piezo1 and its implications for physiology and various pathologies. Biological Reviews, 97 (2). pp.604-614. ISSN 1464-7931

Yang, Shilong and Miao, Xinwen and Arnold, Steven and Li, Boxuan and Ly, Alan T. and Wang, Huan and Wang, Matthew and Guo, Xiangfu and Pathak, Medha M. and Zhao, Wenting and Cox, Charles D. and Shi, Zheng (2022) Membrane curvature governs the distribution of Piezo1 in live cells. Nature Communications, 13 (1). ISSN 2041-1723

Lai, Austin and Thurgood, Peter and Cox, Charles D. and Chheang, Chanly and Peter, Karlheinz and Jaworowski, Anthony and Khoshmanesh, Khashayar and Baratchi, Sara (2022) Piezo1 Response to Shear Stress Is Controlled by the Components of the Extracellular Matrix. ACS Applied Materials & Interfaces, 14 (36). pp.40559-40568. ISSN 1944-8244

Romanov, Valentin and Silvani, Giulia and Zhu, Huiyu and Cox, Charles D. and Martinac, Boris (2021) An Acoustic Platform for Single‐Cell, High‐Throughput Measurements of the Viscoelastic Properties of Cells. Small, 17 (3). p. 2005759. ISSN 1613-6810

Lai, Austin and Chen, Yung C. and Cox, Charles D. and Jaworowski, Anthony and Peter, Karlheinz and Baratchi, Sara (2021) Analyzing the shear‐induced sensitization of mechanosensitive ion channel Piezo‐1 in human aortic endothelial cells. Journal of Cellular Physiology, 236 (4). pp.2976-2987. ISSN 0021-9541

Silvani, Giulia and Romanov, Valentin and Cox, Charles D. and Martinac, Boris (2021) Biomechanical Characterization of Endothelial Cells Exposed to Shear Stress Using Acoustic Force Spectroscopy. Frontiers in Bioengineering and Biotechnology, 9. ISSN 2296-4185

Pineda, Santiago and Nikolova-Krstevski, Vesna and Leimena, Christiana and Atkinson, Andrew J. and Altekoester, Ann-Kristin and Cox, Charles D. and Jacoby, Arie and Huttner, Inken G. and Ju, Yue-Kun and Soka, Magdalena and Ohanian, Monique and Trivedi, Gunjan and Kalvakuri, Sreehari and Birker, Katja and Johnson, Renee and Molenaar, Peter and Kuchar, Dennis and Allen, David G. and van Helden, Dirk F. and Harvey, Richard P. and Hill, Adam P. and Bodmer, Rolf and Vogler, Georg and Dobrzynski, Halina and Ocorr, Karen and Fatkin, Diane (2021) Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, K Ca 1.1, in Sinus Node Function and Arrhythmia Risk. Circulation: Genomic and Precision Medicine, 14 (2). ISSN 2574-8300

Zhang, Yixiao and Angiulli, Gabriella and Martinac, Boris and Cox, Charles D. and Walz, Thomas (2021) Cyclodextrins for structural and functional studies of mechanosensitive channels. Journal of Structural Biology: X, 5. p. 100053. ISSN 25901524

Cox, Charles D. and Zhang, Yixiao and Zhou, Zijing and Walz, Thomas and Martinac, Boris (2021) Cyclodextrins increase membrane tension and are universal activators of mechanosensitive channels. Proceedings of the National Academy of Sciences, 118 (36). pp. e2104820118. ISSN 0027-8424

Kuchel, Philip W. and Romanenko, Konstantin and Shishmarev, Dmitry and Galvosas, Petrik and Cox, Charles D. (2021) Enhanced Ca2+ influx in mechanically distorted erythrocytes measured with 19F nuclear magnetic resonance spectroscopy. Scientific Reports, 11 (1). ISSN 2045-2322

Zhou, Zijing and Li, Jinyuan Vero and Martinac, Boris and Cox, Charles D. (2021) Loss-of-Function Piezo1 Mutations Display Altered Stability Driven by Ubiquitination and Proteasomal Degradation. Frontiers in Pharmacology, 12. ISSN 1663-9812

Li, Jinyuan Vero and Ng, Chai-Ann and Cheng, Delfine and Zhou, Zijing and Yao, Mingxi and Guo, Yang and Yu, Ze-Yan and Ramaswamy, Yogambha and Ju, Lining Arnold and Kuchel, Philip W. and Feneley, Michael P. and Fatkin, Diane and Cox, Charles D. (2021) Modified N-linked glycosylation status predicts trafficking defective human Piezo1 channel mutations. Communications Biology, 4 (1). ISSN 2399-3642

Kuchel, Philip W. and Cox, Charles D. and Daners, Daniel and Shishmarev, Dmitry and Galvosas, Petrik (2021) Surface model of the human red blood cell simulating changes in membrane curvature under strain. Scientific Reports, 11 (1). ISSN 2045-2322

Zhang, Yixiao and Daday, Csaba and Gu, Ruo-Xu and Cox, Charles D. and Martinac, Boris and de Groot, Bert L. and Walz, Thomas (2021) Visualization of the mechanosensitive ion channel MscS under membrane tension. Nature, 590 (7846). pp.509-514. ISSN 0028-0836

Martinac, Boris and Gottlieb, Philip A. and Macmillan, Alexander and Cox, Charles D. and Vassalli, Massimo and Pandzic, Elvis and Ridone, Pietro (2020) Disruption of membrane cholesterol organization impairs the activity of PIEZO1 channel clusters. Journal of General Physiology, 152 (8). ISSN 0022-1295

Martinac, Boris and Nikolaev, Yury A. and Silvani, Giulia and Bavi, Navid and Romanov, Valentin and Nakayama, Yoshitaka and Martinac, Adam D. and Rohde, Paul and Bavi, Omid and Cox, Charles D. (2020) Cell membrane mechanics and mechanosensory transduction. In: Membrane Biomechanics. Elsevier, pp.83-141.

Xue, Feng and Cox, Charles D. and Bavi, Navid and Rohde, Paul R. and Nakayama, Yoshitaka and Martinac, Boris (2020) Membrane stiffness is one of the key determinants of E. coli MscS channel mechanosensitivity. Biochimica et Biophysica Acta (BBA) - Biomembranes, 1862 (5). p. 183203. ISSN 00052736

Buyan, Amanda and Cox, Charles D. and Barnoud, Jonathan and Li, Jinyuan and Chan, Hannah S.M. and Martinac, Boris and Marrink, Siewert J. and Corry, Ben (2020) Piezo1 Forms Specific, Functionally Important Interactions with Phosphoinositides and Cholesterol. Biophysical Journal, 119 (8). pp.1683-1697. ISSN 00063495

Cox, Charles D. and Gottlieb, Philip A. (2019) Amphipathic molecules modulate PIEZO1 activity. Biochemical Society Transactions. ISSN 0300-5127

Cox, Charles D. and Bavi, Navid and Martinac, Boris (2019) Biophysical Principles of Ion-Channel-Mediated Mechanosensory Transduction. Cell Reports, 29 (1). pp.1-12. ISSN 22111247