Waardenberg, Ashley J and Ramialison, Mirana and Bouveret, Romaric and Harvey, Richard P (2014) Genetic networks governing heart development. Cold Spring Harbor Perspectives in Medicine, 4 (11). pp. a013839. ISSN 2157-1422 (OA)
Waardenberg, Ashley J and Ramialison, Mirana and Bouveret, Romaric and Harvey, Richard P (2014) Genetic networks governing heart development. Cold Spring Harbor Perspectives in Medicine, 4 (11). pp. a013839. ISSN 2157-1422 (OA)
Waardenberg, Ashley J and Ramialison, Mirana and Bouveret, Romaric and Harvey, Richard P (2014) Genetic networks governing heart development. Cold Spring Harbor Perspectives in Medicine, 4 (11). pp. a013839. ISSN 2157-1422 (OA)
Abstract
Animal genomes contain a code for construction of the body plan from a fertilized egg. Understanding how genome information is deciphered to create the complex multilayered regulatory systems that drive organismal development, and which become altered in disease, is one of the greatest challenges in the biological sciences. The development of methods that effectively represent and communicate the complexity inherent in gene regulatory networks remains a major barrier. This review introduces the philosophy of systems biology and discusses recent progress in understanding the development of the heart at a systems biology level. (No funders listed)
Metadata
Additional Information: | This article is available for free from the publisher's website (click on link above) |
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Subjects: | R Medicine > R Medicine (General) |
Depositing User: | Repository Administrator |
Date Deposited: | 22 Jan 2016 00:24 |
Last Modified: | 21 Jan 2018 08:48 |