Bosman, Alexis and Edel, Michael J and Blue, Gillian M and Dilley, Rodney J and Harvey, Richard P and Winlaw, David S (2015) Bioengineering and Stem Cell Technology in the Treatment of Congenital Heart Disease. Journal of Clinical Medicine, 4 (4). pp.768-81. ISSN 2077-0383 (OA)
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Abstract
Congenital heart disease places a significant burden on the individual, family and community despite significant advances in our understanding of aetiology and treatment. Early research in ischaemic heart disease has paved the way for stem cell technology and bioengineering, which promises to improve both structural and functional aspects of disease. Stem cell therapy has demonstrated significant improvements in cardiac function in adults with ischaemic heart disease. This finding, together with promising case studies in the paediatric setting, demonstrates the potential for this treatment in congenital heart disease. Furthermore, induced pluripotent stems cell technology, provides a unique opportunity to address aetiological, as well as therapeutic, aspects of disease.
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| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Depositing User: | Repository Administrator |
| Date Deposited: | 21 Jan 2016 21:53 |
| Last Modified: | 28 Sep 2016 05:36 |
| URI: | https://eprints.victorchang.edu.au/id/eprint/209 |
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