The role of frailty in advanced HF and cardiac transplantation

Bart, Nicole K. and Powell, Alice and Macdonald, Peter S. (2023) The role of frailty in advanced HF and cardiac transplantation. Frontiers in Cardiovascular Medicine, 10. ISSN 2297-055X

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Frailty is a complex, multi-system condition often associated with multimorbidity. It has become an important prognostic maker across a range of conditions and is particularly relevant in patients with cardiovascular disease. Frailty encompasses a range of domains including, physical, psychological, and social. There are currently a range of validated tools available to measure frailty. It is an especially important measurement in advanced HF, because frailty occurs in up to 50% of HF patients and is potentially reversible with therapies such as mechanical circulatory support and transplantation. Moreover, frailty is dynamic, and therefore serial measurements are important. This review delves into the measurement of frailty, mechanisms, and its role in different cardiovascular cohorts. Understanding frailty will help determine patients that will benefit from therapies, as well as prognosticate outcomes.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: Repository Administrator
Date Deposited: 27 Apr 2023 03:46
Last Modified: 11 Jul 2023 01:33

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