Efficacy of bortezomib, cyclophosphamide and dexamethasone in cardiac AL amyloidosis

Brennan, Xavier and Withers, Barbara and Jabbour, Andrew and Milliken, Sam and Kotlyar, Eugene and Fay, Keith and Ma, David and Muthiah, Kavitha and Hamad, Nada and Dodds, Anthony and Bart, Nikki and Keogh, Anne and Hayward, Chris and Macdonald, Peter and Moore, John (2022) Efficacy of bortezomib, cyclophosphamide and dexamethasone in cardiac AL amyloidosis. Internal Medicine Journal, 52 (10). pp.1826-1830. ISSN 1444-0903

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Link to published document: http://doi.org/10.1111/imj.15926

Abstract

Cardiac light chain (AL) amyloidosis is a condition with a very poor prognosis. We report a retrospective analysis comparing the traditional melphalan and dexamethasone protocol with cyclophosphamide, bortezomib and dexamethasone in late-stage cardiac AL amyloidosis. The primary end points were overall survival and haematological response. Both regimens provided meaningful responses in this difficult to treat patient group. © 2022 The Authors. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: Repository Administrator
Date Deposited: 01 Mar 2023 03:34
Last Modified: 01 Mar 2023 03:34
URI: http://eprints.victorchang.edu.au/id/eprint/1299

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