Cardiac Resection Injury in Zebrafish

Sheng, Delicia Z. and Zheng, Dawei and Kikuchi, Kazu (2021) Cardiac Resection Injury in Zebrafish. Methods Mol Biol, 2158. pp.63-69. ISSN 1064-3745

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Link to published document: http://doi.org/10.1007/978-1-0716-0668-1_6

Abstract

The zebrafish (Danio rerio) possesses a spectacular capacity for cardiac regeneration. Zebrafish have been used in cardiac regeneration research for nearly two decades, contributing to the identification of signals and cellular mechanisms as potential targets for human heart repair. Investigations into cardiac regeneration in zebrafish have been facilitated by multiple methods of inducing cardiac tissue damage. Among the established methods, cardiac resection injury is a relatively simple, yet robust approach traditionally used to induce cardiac tissue damage in a reproducible manner. Here, we describe a detailed protocol to perform a cardiac resection injury in adult zebrafish and discuss potential complications for researchers who are new to this technique.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: Repository Administrator
Date Deposited: 15 Mar 2021 22:47
Last Modified: 15 Mar 2021 22:47
URI: https://eprints.victorchang.edu.au/id/eprint/1052

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